Expression
- Full suite of expression systems:
E. coli, Yeast, Insect and Mammalian cells - Expression at scale:
- E. coli: up to 400L per week
- Insect cells: up to 200L per week
- Mammalian cells: up to 200L per week
- Yeast cells: 10L fermenter
- "Endotoxin free" environment available for biologics
Purification
- Full suite of chromatographic purification techniques including 60+ Aktas
- Analytical-data-driven purification (HPLC, SEC-RI-MALS, Mass Spec, SDS-Page, CE-SDS)
- Various strategies like refolding, co-purification with Ligands, Binding Partners, etc.
Quality Control and Analytics
- SDS-PAGE, CE-SDS
- HPLC-based methods
- SEC-RI-MALS
- Mass spectrometry including Bruker maXis
- Endotoxin Determination
Ligand-Protein Interaction Analysis
- SPR
- nanoDSF
- Proteros RDA
- MST
- ITC
Structural Biology Suitability Assessment
- Protein crystallography
- Cryo-EM