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Gallery Proteins
High quality "off-the-shelf" proteins
- Access hundreds "off-the-shelf" proteins - rapidly available and ready-to-use, which we call "Gallery Proteins"!
- These represent a selection of potentially relevant drug targets
- Well-established methods and protocols for expression, analytics and QC
- Typical purity levels of > 95% and a homogeneity < 2% aggregation
- Choose from a wide selection of protein target classes including kinases, proteases, gyrases, phosphodiesterases, epigenetic targets, apoptose regulators, growth factors ...
- Product Information Sheet: batch information, concentration, purity, storage buffer details, construct variant, gel image
- Your advantages: established SOPs, secured re-supply, defined specifications, fast access, flexible order amounts
All proteins are for drug discovery in vitro research use only, not for diagnostic, not for therapeutic use.
Gene-to-Protein
"Fit-for-FUNCTION"
- If you have a specific project-demand for a challenging, custom-made protein, Proteros will start with in silico analysis for the right construct design to subsequently express, purify, analyze and QC your protein
- We always work with the final application in mind, whether assay development, screening, profiling, structural analysis (X-Ray crystallography or cryo-EM) or more integrated Discovery Solutions Qualified Hits matters projects
- At Proteros we have got the science and technology platform to deliver the RIGHT challenging protein and complexes. This includes taking care about the right construct, homogeneity, post-translational modifications, complex composition, stability, expression system, right activity and right purity!
Biologics
Expression, Analytics, Characterization, Developability Assessment
Proteros offers “one stop shop” and stand-alone services for complex biologics, that may include:
- Expression (in HEK/CHO cells) of biologics and antigens
- Analytics-driven purification
- Biophysical/biochemical characterization
- Fab/Antigen structure analysis by Protein X-Ray Crystallography
- Structure analysis of high MW complexes by cryo-EM
- Early research developability assessment (non GxP)
At Proteros we are familiar with a broad variety of biologics formats (bs-Ab, ms-Abs, growth factors, non-human antibody formats and antigens) and can deliver the right biologics with accurate assembly, purity, structural and biophysical characterization and early developabilty assessment (non GxP) .
Note: Proteros does not offer biologics related discovery, libraries, engineering, GMP production.
