Supporting Your Search for Novel Chemical Equity and Qualified Hits
First-ever-reported inhibitors of BTK to utilize epoxides as electrophile: A case study in how to identify and validate drug-like leads for difficult-to-target drugs
July 20, 2021 | 11 a.m. EDT
During this webinar, leaders from DNA-encoded chemistry expert X-Chem and protein sciences specialist Proteros discussed:
- How X-Chem and Proteros work together to identify and validate hits
- From library design through to qualified hits
- How they can enhance your drug discovery process
- Drug target BTK case study
- Developing a screen to detect covalent irreversible inhibitors to targets of therapeutic interest
- First-ever-reported inhibitors of BTK to utilize epoxides as electrophile
- The technologies, expertise and scientific insights that made these discoveries possible
